Molecular Medicine Myocardin-Related Transcription Factor A Mediates OxLDL-Induced Endothelial Injury
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منابع مشابه
Myocardin-related transcription factor A mediates OxLDL-induced endothelial injury.
RATIONALE Atherosclerosis proceeds through a multistep reaction that begins with endothelial injury caused by a host of stress signals, among which oxidized low-density lipoprotein (oxLDL) plays a critical role. OxLDL disrupts normal functionality of the endothelium by upregulating adhesion molecules (eg, ICAM-1) and concomitantly downregulating endothelial nitric oxide synthase (eNOS) expressi...
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